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Downregulation of the NHE3-Binding PDZ-Adaptor Protein PDZK1 Expression during Cytokine-Induced Inflammation in Interleukin-10–Deficient Mice

BACKGROUND: Impaired salt and water absorption is an important feature in the pathogenesis of diarrhea in inflammatory bowel disease (IBD). We analyzed the expression of proinflammatory cytokines in the infiltrating immune cells and the function and expression of the Na(+)/H(+) exchanger isoform 3 (...

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Detalhes bibliográficos
Main Authors: Lenzen, Henrike, Lünnemann, Maria, Bleich, Andre, Manns, Michael P., Seidler, Ursula, Jörns, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407152/
https://ncbi.nlm.nih.gov/pubmed/22848392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040657
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