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Normal Cellular Prion Protein Protects against Manganese-induced Oxidative Stress and Apoptotic Cell Death
The normal prion protein is abundantly expressed in the CNS, but its biological function remains unclear. The prion protein has octapeptide repeat regions that bind to several divalent metals, suggesting that the prion proteins may alter the toxic effect of environmental neurotoxic metals. In the pr...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3407037/ https://ncbi.nlm.nih.gov/pubmed/17483122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfm099 |
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