Opposing Role of Prion Protein in Oxidative Stress- and ER Stress-induced Apoptotic Signaling

Although the prion protein is abundantly expressed in the CNS, its biological functions remain unclear. To determine the endogenous function of the cellular prion protein (PrP(c)), we compared the effects of oxidative stress and endoplasmic reticulum (ER) stress inducers on apoptotic signaling in Pr...

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Detalhes bibliográficos
Main Authors: Anantharam, Vellareddy, Kanthasamy, Arthi, Choi, Christopher J, Martin, Dustin P, Latchoumycandane, Calivarathan, Richt, Jüergen A., Kanthasamy, Anumantha G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628483/
https://ncbi.nlm.nih.gov/pubmed/18835352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.08.028
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