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Opposing Role of Prion Protein in Oxidative Stress- and ER Stress-induced Apoptotic Signaling

Although the prion protein is abundantly expressed in the CNS, its biological functions remain unclear. To determine the endogenous function of the cellular prion protein (PrP(c)), we compared the effects of oxidative stress and endoplasmic reticulum (ER) stress inducers on apoptotic signaling in Pr...

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書誌詳細
主要な著者: Anantharam, Vellareddy, Kanthasamy, Arthi, Choi, Christopher J, Martin, Dustin P, Latchoumycandane, Calivarathan, Richt, Jüergen A., Kanthasamy, Anumantha G.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628483/
https://ncbi.nlm.nih.gov/pubmed/18835352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.08.028
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