Milnacipran inhibits glutamatergic N-Methyl-D-Aspartate receptor activity in Spinal Dorsal Horn Neurons

BACKGROUND: Antidepressants, which are widely used for treatment of chronic pain, are thought to have antinociceptive effects by blockade of serotonin and noradrenaline reuptake. However, these drugs also interact with various receptors such as excitatory glutamatergic receptors. Thermal hyperalgesi...

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Main Authors: Kohno, Tatsuro, Kimura, Masafumi, Sasaki, Mika, Obata, Hideaki, Amaya, Fumimasa, Saito, Shigeru
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2012
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407012/
https://ncbi.nlm.nih.gov/pubmed/22716121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-8-45
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