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Neurosteroid dehydroepiandrosterone sulphate enhances pain transmission in rat spinal cord dorsal horn
BACKGROUND: The neurosteroid dehydroepiandrosterone sulphate (DHEAS) activates the sigma-1 receptor, inhibits gamma-aminobutyric acid A (GABA(A)) and glycine receptors, and induces hyperalgesic effects. Although its effects have been studied in various tissues of the nervous system, its synaptic mec...
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| Publicat a: | Br J Anaesth |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6676051/ https://ncbi.nlm.nih.gov/pubmed/31030988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bja.2019.03.026 |
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