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Milnacipran inhibits glutamatergic N-Methyl-D-Aspartate receptor activity in Spinal Dorsal Horn Neurons

BACKGROUND: Antidepressants, which are widely used for treatment of chronic pain, are thought to have antinociceptive effects by blockade of serotonin and noradrenaline reuptake. However, these drugs also interact with various receptors such as excitatory glutamatergic receptors. Thermal hyperalgesi...

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Bibliografische gegevens
Hoofdauteurs: Kohno, Tatsuro, Kimura, Masafumi, Sasaki, Mika, Obata, Hideaki, Amaya, Fumimasa, Saito, Shigeru
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407012/
https://ncbi.nlm.nih.gov/pubmed/22716121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-8-45
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