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Milnacipran inhibits glutamatergic N-Methyl-D-Aspartate receptor activity in Spinal Dorsal Horn Neurons

BACKGROUND: Antidepressants, which are widely used for treatment of chronic pain, are thought to have antinociceptive effects by blockade of serotonin and noradrenaline reuptake. However, these drugs also interact with various receptors such as excitatory glutamatergic receptors. Thermal hyperalgesi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kohno, Tatsuro, Kimura, Masafumi, Sasaki, Mika, Obata, Hideaki, Amaya, Fumimasa, Saito, Shigeru
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407012/
https://ncbi.nlm.nih.gov/pubmed/22716121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-8-45
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