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To the rescue: The Fanconi Anemia genome stability pathway salvages replication forks
DNA damage can arrest replication forks during S phase. Failure to stabilize and restart arrested forks results in fork collapse and genomic instability. In this issue of Cancer Cell, Schlacher et al show that the Fanconi Anemia and BRCA2 tumor suppressor pathways cooperate to protect stalled replic...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3406730/ https://ncbi.nlm.nih.gov/pubmed/22789533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.06.006 |
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