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Fibroblast Growth Factor 21 (FGF21) Inhibits Chondrocyte Function and Growth Hormone Action Directly at the Growth Plate

Fibroblast growth factor 21 (FGF21) modulates glucose and lipid metabolism during fasting. In addition, previous evidence indicates that increased expression of FGF21 during chronic food restriction is associated with reduced bone growth and growth hormone (GH) insensitivity. In light of the inhibit...

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Detalhes bibliográficos
Main Authors: Wu, Shufang, Levenson, Amy, Kharitonenkov, Alexei, De Luca, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406689/
https://ncbi.nlm.nih.gov/pubmed/22696219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.343707
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