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TLRs innate immunereceptors and Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) CIDR1α-driven human polyclonal B-cell activation

Chronic malaria severely affects the immune system and causes polyclonal B-cell activation, as evidenced by the presence of hypergammaglobulinemia, elevated levels of autoantibodies, loss of B-cell memory and the frequent occurrence of Burkitt’s lymphomas (BL) in children living in malaria endemic a...

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Detalhes bibliográficos
Main Authors: Simone, Olivia, Bejarano, Maria Teresa, Pierce, Susan K., Antonaci, Salvatore, Wahlgren, Mats, Troye-Blomberg, Marita, Donati, Daria
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406598/
https://ncbi.nlm.nih.gov/pubmed/21620790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actatropica.2011.05.005
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