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Binding of Subdomains 1/2 of PfEMP1-DBL1α to Heparan Sulfate or Heparin Mediates Plasmodium falciparum Rosetting

The capacity of Plasmodium falciparum parasitized erythrocytes (pRBC) to adhere to the endothelial lining in the microvasculature and to red blood cells (RBC) is associated with the virulence of the parasite, the pathogenesis and development of severe malaria. Rosetting, the binding of uninfected RB...

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Pubblicato in:PLoS One
Autori principali: Angeletti, Davide, Sandalova, Tatyana, Wahlgren, Mats, Achour, Adnane
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351205/
https://ncbi.nlm.nih.gov/pubmed/25742651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118898
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