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Binding of Subdomains 1/2 of PfEMP1-DBL1α to Heparan Sulfate or Heparin Mediates Plasmodium falciparum Rosetting

The capacity of Plasmodium falciparum parasitized erythrocytes (pRBC) to adhere to the endothelial lining in the microvasculature and to red blood cells (RBC) is associated with the virulence of the parasite, the pathogenesis and development of severe malaria. Rosetting, the binding of uninfected RB...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Angeletti, Davide, Sandalova, Tatyana, Wahlgren, Mats, Achour, Adnane
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351205/
https://ncbi.nlm.nih.gov/pubmed/25742651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118898
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