Longitudinal analysis of naturally acquired PfEMP1 CIDR domain variant antibodies identifies associations with malaria protection

BACKGROUND: Malaria pathogenicity is determined, in part, by the adherence of Plasmodium falciparum–infected erythrocytes to the microvasculature mediated via specific interactions between P. falciparum erythrocyte membrane protein (PfEMP1) variant domains and host endothelial receptors. Naturally a...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Obeng-Adjei, Nyamekye, Larremore, Daniel B., Turner, Louise, Ongoiba, Aissata, Li, Shanping, Doumbo, Safiatou, Yazew, Takele B., Kayentao, Kassoum, Miller, Louis H., Traore, Boubacar, Pierce, Susan K., Buckee, Caroline O., Lavstsen, Thomas, Crompton, Peter D., Tran, Tuan M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406271/
https://ncbi.nlm.nih.gov/pubmed/32427581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.137262
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