Longitudinal analysis of naturally acquired PfEMP1 CIDR domain variant antibodies identifies associations with malaria protection

BACKGROUND: Malaria pathogenicity is determined, in part, by the adherence of Plasmodium falciparum–infected erythrocytes to the microvasculature mediated via specific interactions between P. falciparum erythrocyte membrane protein (PfEMP1) variant domains and host endothelial receptors. Naturally a...

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Dettagli Bibliografici
Pubblicato in:JCI Insight
Autori principali: Obeng-Adjei, Nyamekye, Larremore, Daniel B., Turner, Louise, Ongoiba, Aissata, Li, Shanping, Doumbo, Safiatou, Yazew, Takele B., Kayentao, Kassoum, Miller, Louis H., Traore, Boubacar, Pierce, Susan K., Buckee, Caroline O., Lavstsen, Thomas, Crompton, Peter D., Tran, Tuan M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2020
Soggetti:
Clinical Medicine
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406271/
https://ncbi.nlm.nih.gov/pubmed/32427581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.137262
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