Genomic evolution in Barrett’s adenocarcinoma cells: critical roles of elevated hsRAD51, homologous recombination and Alu sequences in the genome

A prominent feature of most cancers including Barrett’s adenocarcinoma (BAC) is genetic instability, which is associated with development and progression of disease. In this study, we investigated the role of recombinase (hsRAD51), a key component of homologous recombination (HR)/repair, in evolving...

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Autors principals: Pal, J, Bertheau, R, Buon, L, Qazi, A, Batchu, RB, Bandyopadhyay, S, Ali-Fehmi, R, Beer, DG, Weaver, DW, Reis, RJ Shmookler, Goyal, RK, Huang, Q, Munshi, NC, Shammas, MA
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406293/
https://ncbi.nlm.nih.gov/pubmed/21423218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.83
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