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Ochronosis in a murine model of alkaptonuria is synonymous to that in the human condition

OBJECTIVE: Alkaptonuria (AKU) is a rare genetic disease which results in severe early onset osteoarthropathy. It has recently been shown that the subchondral interface is of key significance in disease pathogenesis. Human surgical tissues are often beyond this initial stage and there is no published...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Taylor, A.M., Preston, A.J., Paulk, N.K., Sutherland, H., Keenan, C.M., Wilson, P.J.M., Wlodarski, B., Grompe, M., Ranganath, L.R., Gallagher, J.A., Jarvis, J.C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406176/
https://ncbi.nlm.nih.gov/pubmed/22542924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2012.04.013
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