Ochronosis in a murine model of alkaptonuria is synonymous to that in the human condition

OBJECTIVE: Alkaptonuria (AKU) is a rare genetic disease which results in severe early onset osteoarthropathy. It has recently been shown that the subchondral interface is of key significance in disease pathogenesis. Human surgical tissues are often beyond this initial stage and there is no published...

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Autori principali: Taylor, A.M., Preston, A.J., Paulk, N.K., Sutherland, H., Keenan, C.M., Wilson, P.J.M., Wlodarski, B., Grompe, M., Ranganath, L.R., Gallagher, J.A., Jarvis, J.C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406176/
https://ncbi.nlm.nih.gov/pubmed/22542924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2012.04.013
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