MAP-Kinase Regulated Cytosolic Phospholipase A2 Activity Is Essential for Production of Infectious Hepatitis C Virus Particles

Hepatitis C virus (HCV) has infected around 160 million individuals. Current therapies have limited efficacy and are fraught with side effects. To identify cellular HCV dependency factors, possible therapeutic targets, we manipulated signaling cascades with pathway-specific inhibitors. Using this ap...

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Autores principales: Menzel, Nicolas, Fischl, Wolfgang, Hueging, Kathrin, Bankwitz, Dorothea, Frentzen, Anne, Haid, Sibylle, Gentzsch, Juliane, Kaderali, Lars, Bartenschlager, Ralf, Pietschmann, Thomas
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406102/
https://ncbi.nlm.nih.gov/pubmed/22911431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002829
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