Apolipoprotein E Codetermines Tissue Tropism of Hepatitis C Virus and Is Crucial for Viral Cell-to-Cell Transmission by Contributing to a Postenvelopment Step of Assembly

Hepatitis C virus (HCV) predominantly infects human hepatocytes, although extrahepatic virus reservoirs are being discussed. Infection of cells is initiated via cell-free and direct cell-to-cell transmission routes. Cell type-specific determinants of HCV entry and RNA replication have been reported....

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Main Authors: Hueging, Kathrin, Doepke, Mandy, Vieyres, Gabrielle, Bankwitz, Dorothea, Frentzen, Anne, Doerrbecker, Juliane, Gumz, Frauke, Haid, Sibylle, Wölk, Benno, Kaderali, Lars, Pietschmann, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911621/
https://ncbi.nlm.nih.gov/pubmed/24173232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01815-13
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