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Noscapine Induced Apoptosis via Downregulation of Survivin in Human Neuroblastoma Cells Having Wild Type or Null p53

Neuroblastoma is the most common extracranial solid tumor of childhood. It accounts for 15% of pediatric cancer deaths. Chemotherapy is the mainstay of treatment in children with advanced neuroblastoma. Noscapine, a nontoxic natural compound, can trigger apoptosis in many cancer types. We now show t...

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書誌詳細
主要な著者: Li, Shiwang, He, Jing, Li, Shuai, Cao, Guoqing, Tang, Shaotao, Tong, Qiangsong, Joshi, Harish C.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406069/
https://ncbi.nlm.nih.gov/pubmed/22848370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040076
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