Let-7b/c Enhance the Stability of a Tissue-Specific mRNA during Mammalian Organogenesis as Part of a Feedback Loop Involving KSRP

Gene silencing mediated by either microRNAs (miRNAs) or Adenylate/uridylate-rich elements Mediated mRNA Degradation (AMD) is a powerful way to post-transcriptionally modulate gene expression. We and others have reported that the RNA–binding protein KSRP favors the biogenesis of select miRNAs (includ...

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Detalhes bibliográficos
Principais autores: Repetto, Emanuela, Briata, Paola, Kuziner, Nathalie, Harfe, Brian D., McManus, Michael T., Gherzi, Roberto, Rosenfeld, Michael G., Trabucchi, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405994/
https://ncbi.nlm.nih.gov/pubmed/22844247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002823
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