PDGFR-α Inhibition Preserves Blood-Brain Barrier after Intracerebral Hemorrhage

OBJECTIVE: Perihematomal edema results from disruption of the blood-brain barrier (BBB) by key mediators, such as thrombin, following intracerebral hemorrhage (ICH). Platelet derived growth factor receptor alpha (PDGFR-α), a tyrosine kinase receptor, was found in previous studies to play a role in o...

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Bibliografiset tiedot
Päätekijät: Ma, Qingyi, Huang, Bin, Khatibi, Nikan, Rolland, William, Suzuki, Hidenori, Zhang, John H., Tang, Jiping
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405848/
https://ncbi.nlm.nih.gov/pubmed/22190365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22549
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