Fibroblast growth factors preserve blood-brain barrier integrity through RhoA inhibition after intracerebral hemorrhage in mice

Fibroblast growth factors (FGFs) maintain and promote vascular integrity; however whether FGFs protect the blood-brain barrier (BBB) after intracerebral hemorrhage (ICH) remains unexplored. In this present study, we hypothesized that exogenous FGF administration attenuates brain injury after ICH, sp...

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Detalhes bibliográficos
Main Authors: Huang, Bin, Krafft, Paul R., Ma, Qingyi, Rolland, William B., Caner, Basak, Lekic, Tim, Manaenko, Anatol, Le, Mai, Tang, Jiping, Zhang, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299916/
https://ncbi.nlm.nih.gov/pubmed/22300708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2012.01.008
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