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PDGFR-α Inhibition Preserves Blood-Brain Barrier after Intracerebral Hemorrhage
OBJECTIVE: Perihematomal edema results from disruption of the blood-brain barrier (BBB) by key mediators, such as thrombin, following intracerebral hemorrhage (ICH). Platelet derived growth factor receptor alpha (PDGFR-α), a tyrosine kinase receptor, was found in previous studies to play a role in o...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3405848/ https://ncbi.nlm.nih.gov/pubmed/22190365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22549 |
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