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IL-2 Family Cytokines: New Insights into the Complex Roles of IL-2 as a Broad Regulator of T helper Cell Differentiation

Interleukin-2 (IL-2) is a pleiotropic cytokine that drives T-cell growth, augments NK cytolytic activity, induces the differentiation of regulatory T cells, and mediates activation-induced cell death. Along with IL-4, IL-7, IL-9, IL-15, and IL-21, IL-2 shares the common cytokine receptor γ chain, γ(...

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Bibliografiske detaljer
Main Authors: Liao, Wei, Lin, Jian-Xin, Leonard, Warren J.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405730/
https://ncbi.nlm.nih.gov/pubmed/21889323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2011.08.003
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