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FolX from Pseudomonas aeruginosa is octameric in both crystal and solution

FolX encodes an epimerase that forms one step of the tetrahydrofolate biosynthetic pathway, which is of interest as it is an established target for important drugs. Here we report the crystal structure of FolX from the bacterial opportunistic pathogen Pseudomonas aeruginosa, as well as a detailed an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gabrielsen, Mads, Beckham, Katherine S.H., Cogdell, Richard J., Byron, Olwyn, Roe, Andrew J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier Science B.V 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405516/
https://ncbi.nlm.nih.gov/pubmed/22575651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.03.031
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