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FolX from Pseudomonas aeruginosa is octameric in both crystal and solution
FolX encodes an epimerase that forms one step of the tetrahydrofolate biosynthetic pathway, which is of interest as it is an established target for important drugs. Here we report the crystal structure of FolX from the bacterial opportunistic pathogen Pseudomonas aeruginosa, as well as a detailed an...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier Science B.V
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3405516/ https://ncbi.nlm.nih.gov/pubmed/22575651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.03.031 |
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