VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd

Regulation of vascular endothelial (VE) growth factor (VEGF)–induced permeability is critical in physiological and pathological processes. We show that tyrosine phosphorylation of VEGF receptor 2 (VEGFR2) at Y951 facilitates binding of VEGFR2 to the Rous sarcoma (Src) homology 2-domain of T cell–spe...

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Главные авторы: Sun, Zuyue, Li, Xiujuan, Massena, Sara, Kutschera, Simone, Padhan, Narendra, Gualandi, Laura, Sundvold-Gjerstad, Vibeke, Gustafsson, Karin, Choy, Wing Wen, Zang, Guangxiang, Quach, My, Jansson, Leif, Phillipson, Mia, Abid, Md Ruhul, Spurkland, Anne, Claesson-Welsh, Lena
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405501/
https://ncbi.nlm.nih.gov/pubmed/22689825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111343
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