VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd

Regulation of vascular endothelial (VE) growth factor (VEGF)–induced permeability is critical in physiological and pathological processes. We show that tyrosine phosphorylation of VEGF receptor 2 (VEGFR2) at Y951 facilitates binding of VEGFR2 to the Rous sarcoma (Src) homology 2-domain of T cell–spe...

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Autores principales: Sun, Zuyue, Li, Xiujuan, Massena, Sara, Kutschera, Simone, Padhan, Narendra, Gualandi, Laura, Sundvold-Gjerstad, Vibeke, Gustafsson, Karin, Choy, Wing Wen, Zang, Guangxiang, Quach, My, Jansson, Leif, Phillipson, Mia, Abid, Md Ruhul, Spurkland, Anne, Claesson-Welsh, Lena
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405501/
https://ncbi.nlm.nih.gov/pubmed/22689825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111343
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