T Cell Specific Adapter Protein (TSAd) Interacts with Tec Kinase ITK to Promote CXCL12 Induced Migration of Human and Murine T Cells

BACKGROUND: The chemokine CXCL12/SDF-1α interacts with its G-protein coupled receptor CXCR4 to induce migration of lymphoid and endothelial cells. T cell specific adapter protein (TSAd) has been found to promote migration of Jurkat T cells through interaction with the G protein β subunit. However, t...

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Main Authors: Berge, Tone, Sundvold-Gjerstad, Vibeke, Granum, Stine, Andersen, Thorny C. B., Holthe, Gunn B., Claesson-Welsh, Lena, Andreotti, Amy H., Inngjerdingen, Marit, Spurkland, Anne
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841202/
https://ncbi.nlm.nih.gov/pubmed/20305788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009761
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