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Regulation of mitochondrial permeability transition pore by PINK1
BACKGROUND: Loss-of-function mutations in PTEN-induced kinase 1 (PINK1) have been linked to familial Parkinson’s disease, but the underlying pathogenic mechanism remains unclear. We previously reported that loss of PINK1 impairs mitochondrial respiratory activity in mouse brains. RESULTS: In this st...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3405481/ https://ncbi.nlm.nih.gov/pubmed/22630785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-7-22 |
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