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Role in translation of a triple tandemly repeated sequence in the 5'-untranslated region of human thymidylate synthase mRNA.

A triple tandem repeat (TTR) consisting of 90 nucleotides exists immediately upstream of the ATG initiator codon in human thymidylate synthase (TS) cDNA (pcHTS-1). To investigate the role of the TTR in the expression of the TS cDNA, we used pcHTS-1 to construct mutant cDNA clones in which part of th...

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Udgivet i:Nucleic Acids Res
Principais autores: Kaneda, S, Takeishi, K, Ayusawa, D, Shimizu, K, Seno, T, Altman, S
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1987
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC340522/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3029702/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.3.1259
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