Role in translation of a triple tandemly repeated sequence in the 5'-untranslated region of human thymidylate synthase mRNA.

A triple tandem repeat (TTR) consisting of 90 nucleotides exists immediately upstream of the ATG initiator codon in human thymidylate synthase (TS) cDNA (pcHTS-1). To investigate the role of the TTR in the expression of the TS cDNA, we used pcHTS-1 to construct mutant cDNA clones in which part of th...

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Hauptverfasser: Kaneda, S, Takeishi, K, Ayusawa, D, Shimizu, K, Seno, T, Altman, S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1987
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC340522/
https://ncbi.nlm.nih.gov/pubmed/3029702
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