Induction, by thymidylate stress, of genetic recombination as evidenced by deletion of a transferred genetic marker in mouse FM3A cells.

Studies were made on the genetic consequences of methotrexate-directed thymidylate stress, focusing attention on a human thymidylate synthase gene that was introduced as a heterologous genetic marker into mouse thymidylate synthase-negative mutant cells. Thymidylate stress induced thymidylate syntha...

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Bibliographic Details
Main Authors: Ayusawa, D, Koyama, H, Shimizu, K, Kaneda, S, Takeishi, K, Seno, T
Format: Artigo
Language:Inglês
Published: 1986
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC367094/
https://ncbi.nlm.nih.gov/pubmed/3796589
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