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The alpha protein ICP0 does not appear to play a major role in the regulation of herpes simplex virus gene expression during infection in tissue culture.

The herpes simplex virus type 1 (HSV-1) alpha protein ICP0 trans-activates HSV-1 early genes in transient expression assays. To investigate the function of ICP0 during HSV-1 infection, we have lowered the level of ICP0 by use of a recombinant plasmid that has been engineered to express the antisense...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Sandri-Goldin, R M, Sekulovich, R E, Leary, K
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1987
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC340497/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3029709/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.3.905
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