The regions important for the activator and repressor functions of herpes simplex virus type 1 alpha protein ICP27 map to the C-terminal half of the molecule.

Samankaltaisia teoksia

• The herpes simplex virus type 1 alpha protein ICP27 can act as a trans-repressor or a trans-activator in combination with ICP4 and ICP0.
  Tekijä: Sekulovich, R E, et al.
  Julkaistu: (1988)
• Mutations in the activation region of herpes simplex virus regulatory protein ICP27 can be trans dominant.
  Tekijä: Smith, I L, et al.
  Julkaistu: (1991)
• The herpes simplex virus regulatory protein ICP27 contributes to the decrease in cellular mRNA levels during infection.
  Tekijä: Hardwicke, M A, et al.
  Julkaistu: (1994)
• The C-terminal repressor region of herpes simplex virus type 1 ICP27 is required for the redistribution of small nuclear ribonucleoprotein particles and splicing factor SC35; however, these alterations are not sufficient to inhibit host cell splicing.
  Tekijä: Sandri-Goldin, R M, et al.
  Julkaistu: (1995)
• The alpha protein ICP0 does not appear to play a major role in the regulation of herpes simplex virus gene expression during infection in tissue culture.
  Tekijä: Sandri-Goldin, R M, et al.
  Julkaistu: (1987)