The regions important for the activator and repressor functions of herpes simplex virus type 1 alpha protein ICP27 map to the C-terminal half of the molecule.

The herpes simplex virus type 1 (HSV-1) alpha or immediate-early proteins ICP4 (IE175), ICP0 (IE110), and ICP27 (IE63) are trans-acting proteins which affect HSV-1 gene expression. We previously showed that ICP27 in combination with ICP4 and ICP0 could act as a repressor or an activator in transfect...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Hardwicke, M A, Vaughan, P J, Sekulovich, R E, O'Conner, R, Sandri-Goldin, R M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC251092/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2552143/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.11.4590-4602.1989
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