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The alpha protein ICP0 does not appear to play a major role in the regulation of herpes simplex virus gene expression during infection in tissue culture.

The herpes simplex virus type 1 (HSV-1) alpha protein ICP0 trans-activates HSV-1 early genes in transient expression assays. To investigate the function of ICP0 during HSV-1 infection, we have lowered the level of ICP0 by use of a recombinant plasmid that has been engineered to express the antisense...

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Bibliographic Details
Main Authors: Sandri-Goldin, R M, Sekulovich, R E, Leary, K
Format: Artigo
Language:Inglês
Published: 1987
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC340497/
https://ncbi.nlm.nih.gov/pubmed/3029709
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