A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase

Ubiquitination of histones plays a critical role in the regulation of several processes within the nucleus, including maintenance of genome stability and transcriptional regulation. The only known ubiquitination site on histones is represented by a conserved Lys residue located at the C terminus of...

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Main Authors: Gatti, Marco, Pinato, Sabrina, Maspero, Elena, Soffientini, Paolo, Polo, Simona, Penengo, Lorenza
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404880/
https://ncbi.nlm.nih.gov/pubmed/22713238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.20919
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