Modulation of HIV pathogenesis and T-cell signaling by HIV-1 Nef

HIV-1 Nef protein is an approximately 27-kDa myristoylated protein that is a virulence factor essential for efficient viral replication and infection in CD4(+) T cells. The functions of CD4(+) T cells are directly impeded after HIV infection. HIV-1 Nef plays a crucial role in manipulating host cellu...

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Bibliografiske detaljer
Main Authors: Saxena, Shailendra K, Shrivastava, Gaurav, Tiwari, Sneham, Swamy, ML Arvinda, Nair, Madhavan PN
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404840/
https://ncbi.nlm.nih.gov/pubmed/22844345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/FVL.12.42
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