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HIV-1 Nef: a multifaceted modulator of T cell receptor signaling

Nef, an accessory protein of the Human Immunodeficiency Virus type 1 (HIV-1), is dispensable for viral replication in cell culture, but promotes virus replication and pathogenesis in the infected host. Acting as protein-interaction adaptor, HIV-1 Nef modulates numerous target cell activities includi...

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Bibliografiske detaljer
Main Authors: Abraham, Libin, Fackler, Oliver T
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534016/
https://ncbi.nlm.nih.gov/pubmed/23227982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-10-39
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