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Aggregatibacter actinomycetemcomitans leukotoxin is post-translationally modified by addition of either saturated or hydroxylated fatty acyl chains

Aggregatibacter actinomycetemcomitans, a common inhabitant of the human upper aerodigestive tract, produces a repeat in toxin (RTX), leukotoxin (LtxA). The LtxA is transcribed as a 114-kDa inactive protoxin with activation being achieved by attachment of short chain fatty acyl groups to internal lys...

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Detalhes bibliográficos
Main Authors: Fong, K.P., Tang, H.-Y., Brown, A.C., Kieba, I.R., Speicher, D.W., Boesze-Battaglia, K., Lally, E.T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404814/
https://ncbi.nlm.nih.gov/pubmed/21729247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.2041-1014.2011.00617.x
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