Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice

Previous studies have found that inappropriate elevation of matrix metalloproteinase-9 (MMP9) expression and activity is coincident with early onset of emphysema in Smad3-null mice. Herein, we further investigated the role of increased MMP9 in emphysema pathogenesis and the related molecular regulat...

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Main Authors: Xu, Bing, Chen, Hui, Xu, Wei, Zhang, Wenming, Buckley, Sue, Zheng, Song Guo, Warburton, David, Kolb, Martin, Gauldie, Jack, Shi, Wei
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2012
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404628/
https://ncbi.nlm.nih.gov/pubmed/22610349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00060.2012
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