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Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice
Previous studies have found that inappropriate elevation of matrix metalloproteinase-9 (MMP9) expression and activity is coincident with early onset of emphysema in Smad3-null mice. Herein, we further investigated the role of increased MMP9 in emphysema pathogenesis and the related molecular regulat...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3404628/ https://ncbi.nlm.nih.gov/pubmed/22610349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00060.2012 |
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