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Transient Overexpression of Gremlin Results in Epithelial Activation and Reversible Fibrosis in Rat Lungs
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic disease of the lung parenchyma, without curative treatment. Gremlin is a bone morphogenic protein (BMP) antagonist, its expression being increased in IPF lungs. It has been implicated in promoting myofibroblast accumulation, likely throug...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Thoracic Society
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3135847/ https://ncbi.nlm.nih.gov/pubmed/20705941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0070OC |
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