VEGF ameliorates pulmonary hypertension through inhibition of endothelial apoptosis in experimental lung fibrosis in rats

Idiopathic pulmonary fibrosis (IPF) can lead to the development of secondary pulmonary hypertension (PH) and ultimately death. Despite this known association, the precise mechanism of disease remains unknown. Using a rat model of IPF, we explored the role of the proangiogenic and antiapoptotic growt...

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Bibliographic Details
Main Authors: Farkas, Laszlo, Farkas, Daniela, Ask, Kjetil, Möller, Antje, Gauldie, Jack, Margetts, Peter, Inman, Mark, Kolb, Martin
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673845/
https://ncbi.nlm.nih.gov/pubmed/19381013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36136
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