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Robust expansion of human hepatocytes in Fah(−/−)/Rag2(−/−)/Il2rg (−/−) mice
Mice that could be highly repopulated with human hepatocytes would have many potential uses in drug development and research applications. The best available model of liver humanization, the uroplasminogen-activator transgenic model, has major practical limitations. To provide a broadly useful hepat...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3404624/ https://ncbi.nlm.nih.gov/pubmed/17664939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt1326 |
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