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Fluorescence lifetime imaging of activatable target specific molecular probes

In vivo optical imaging using fluorescently labeled self-quenched monoclonal antibodies, activated through binding and internalization within target cells, results in excellent target-to-background ratios. We hypothesized that these molecular probes could be utilized to accurately report on cellular...

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Bibliographic Details
Main Authors: Alford, Raphael, Ogawa, Mikako, Hassan, Moinuddin, Gandjbakhche, Amir H., Choyke, Peter L., Kobayashi, Hisataka
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404610/
https://ncbi.nlm.nih.gov/pubmed/20101762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmmi.360
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