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Subcellular relocation of histone deacetylase 4 regulates growth plate chondrocyte differentiation through Ca(2+)/calmodulin-dependent kinase IV
Regulatory mechanisms of chondrocyte differentiation in the growth plate are incompletely understood. Here, we find that histone deacetylase 4 (HDAC4) is located in the nucleus of chondrocytes in the proliferation zone and relocates to the cytoplasm of chondrocytes in the prehypertrophic zone in viv...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3404523/ https://ncbi.nlm.nih.gov/pubmed/22442139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00348.2011 |
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