Cyclic Equibiaxial Tensile Strain Alters Gene Expression of Chondrocytes via Histone Deacetylase 4 Shuttling

OBJECTIVES: This paper aims to investigate whether equibiaxial tensile strain alters chondrocyte gene expression via controlling subcellular localization of histone deacetylase 4 (HDAC4). MATERIALS AND METHODS: Murine chondrocytes transfected with GFP-HDAC4 were subjected to 3 h cyclic equibiaxial t...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chen, Chongwei, Wei, Xiaochun, Lv, Zhi, Sun, Xiaojuan, Wang, Shaowei, Zhang, Yang, Jiao, Qiang, Wang, Xiaohu, Li, Yongping, Wei, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858146/
https://ncbi.nlm.nih.gov/pubmed/27149270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154951
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