Subcellular relocation of histone deacetylase 4 regulates growth plate chondrocyte differentiation through Ca(2+)/calmodulin-dependent kinase IV

Regulatory mechanisms of chondrocyte differentiation in the growth plate are incompletely understood. Here, we find that histone deacetylase 4 (HDAC4) is located in the nucleus of chondrocytes in the proliferation zone and relocates to the cytoplasm of chondrocytes in the prehypertrophic zone in viv...

Full description

Saved in:
Bibliographic Details
Main Authors: Guan, Yingjie, Chen, Qian, Yang, Xu, Haines, Paul, Pei, Ming, Terek, Richard, Wei, Xiaochun, Zhao, Tingcun, Wei, Lei
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404523/
https://ncbi.nlm.nih.gov/pubmed/22442139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00348.2011
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items